Q : Will such long hours on the road led to engine overheating ?
A : No.
Q : what are the indicator should my Nissan Latio gets overheated?
A : Refer to speedometer on the left gauge, beside 'Cruise' and 'Set',
the best is to refer owner manual.
Q : What is the cause led to engine overheating?
A : Frequently, Radiator leak, Fan motor. Sometime water pump, Thermostate.
Q : Will such long hours on the road led to wear & tear more faster then usual?
A : I will say Yes, but I don't have data to prove that I am right.